In short, no, it shouldn't make any difference once the LFS system is finished.
I say "shouldn't" because it will depend on how you configure your kernel - if you select the proper USB support.
Also, you do not have to use the LFS live CD. I've built an LFS system using Knoppix more than once before. The benefit of the LFS Live CD is it's minimal (memory/CPU) and comes with all the source tarballs you need. You can crank up Knoppix, parition your drive(s), create a filesystem, set up the network, download the tarballs to the hard drive, and get started. There used to be a wget file that included all the packages. You'd open a console in Knoppix and type something like "wget --input-file=package_list.txt" and wget would start downloading all the tarballs. You might have to do some searching to find that file, or you could just create it yourself.
Anyway, the point is, you can build an LFS system without the LFS Live CD. It's not a requirement.
Last edited by Dark_Helmet; 10-24-2005 at 01:54 AM.