Sending I2C msg from SMBus to MCU

Hello,

I'm running vanilla 3.2.38 on Intel's ATOM.
After running sensors-detect I have /dev/i2c-0

One of the slave devices connected to the BUS is TI's microcontroller (MSP430F5529) that waits for I2C message.

It's slave address is 0x43.

I opened the controller with:

        int Handle = open ("/dev/i2c-0",O_RDWR);
	if (Handle < 0)
	{
		printf ("Failed to open smbus\n");
		return -1;
	}

Now I have to write a 16 bytes message to the slave.

How can I tell the kernel to write to slave address 0x43 ?

The message can be longer than 32 bytes.

should I use:

BytesWritten = write(Handle, WriteBuffer, sizeof(WriteBuffer));

Thanks,
Zvika