B-Pi with Android 4.2 / I2C / crosscompiling

Hello again,

i´m exploring a way to use I2C on a B-Pi with Android 4.2.
I have read, that in order to do this by userspace code i need to invoke i2c-dev.h, which in return includes other linux headers.

1.) Is it possible to crosscompile programms when planing to use I2C?

2.) In case yes, i probably have to use a linux Host or a linux in a VM, since a Windows PC probably has no clue of things like
#include <linux/types.h>
#include <linux/i2c.h>
etc... ????

best regards,
Jasson