Generally speaking, yes. The checksum is computed using integer summations on the bytes on the disk. I suppose it's possible hat the Mac integer arithmetic differers from that of the Intel chip, so the checksum might be computed differently. Can you try your disk(s) on an Intel system to see if the results are any different? (Honestly, I think that's a wild shot, but, if it's easy, why not try it?)
Oh, are you intending to install Fedora on your Mac? (Mine is an Intel system, so I've never looked into Mac distributions. In fact, I didn't even know that there was one available.)
Oh, if your download is bad, there are many different mirror sites you can try, and I believe that there is also some BitTorrent downloads available.