Keybindings probably wouldn't help you. They let you define which physical key matches which character you want it to type, but mouse functions are handled by a separate driver and configured differently.
kde has a built-in mouse navigation function. You can enable it in the control center's mouse settings with the number pad.
A quick search of apt turned up keynav
, which seems to have a neat, advanced way of navigating the desktop. It'd probably take some getting used to, but I'll bet it's lightning fast once you do.