I recently added to a laptop a second SATA Hitachi hard disk (HDD) using a HDD caddy that replaced the CD/DVD drive. This second HDD was from an old laptop whose motherboard died and had a Windows Vista partition and a linux partition.
The first HDD (Toshiba) in the laptop was partitioned as follows:
/dev/sda1 for the swap
/dev/sda2 for the root directory of Slackware 14.1 64bit with ext4 filesystem
After adding the second HDD, the boot process failed...